It is not possible to diagnose the existence of rheumatoid arthritis beforehand. Although it is a hereditary disease, there are several factors, both environmental and biological, which may also trigger the onset of this debilitating disease. Similarly, the factors can be suppressed for sometime by the reversal of the relevant causes.

One of the most important and noteworthy causes of rheumatoid arthritis is the destruction of the gut bacteria which is healthy in a number of ways. Consuming too many antibiotics also leads to the disruption of friendly bacteria; emotional trauma is also one main cause. This is mainly due to the strong impact of stress on the gut. If these useful bacteria get imbalanced even once, it will take years to re-balance it. Furthermore, there must be something helpful and effective to fix this problem. If this re-balancing of gut bacteria takes place, it will initiate in lessening the symptoms and severity of rheumatoid arthritis. The only solution to fix this problem is to ensure intake of healthy bacteria through diet on a daily basis.

Foods containing live culture bacteria have healthy impact on the immune system of the body, which in turn prevents it from malfunctioning. Yoghurt containing live culture bacteria in it has a good deal of beneficial effects. There are an infinite number of sources which contain probiotics, and can also be artificially made by you without any difficulty. Thus, probiotics must be incorporated in your everyday diet. Dairy products are a good and easy source of probiotics. They can be consumed through yoghurt, kefir, and many other dairy products. Those who are not fond of dairy products can still get probiotic supplements through innumerable foods.

An important source of non-dairy probiotic supplement is available in most markets in the form of cultured coconut milk. Homemade cultured coconut milk, soy milk, and rice milk or fruit juice made from kefir grains is also a good source of probiotic supplements and as such, can be used for treating RA. Unpasteurised sauerkraut, sour pickles, vegetable ferments such as sour turnips, fermented radish, potato cheese are also healthy sources.

Probiotic food supplements are either made from an established culture which can be either bought or captured wild bacteria from the air such as sauerkraut, kim chee, sour pickles, other vegetable ferments, brines, and porridge. Thus, probiotic supplements are highly beneficial in balancing the gut flora and reversing the symptoms experienced by people suffering from rheumatoid arthritis.

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what is rheumatoid arthritis genetic

31 thoughts on “What Is Rheumatoid Arthritis Genetic

  1. Tasha Marie

    I have a rheumatoid factor of 8.9, and he told me 11 is positive?
    I am 20 years old and the dr says I have signs of an inflammatory illness in my blood test results. What could this mean? My mother has rheumatoid arthritis, if family history means anything. I have had severe joint and muscle pain over the last couple months?

    1. Daniel Ogas

      This could mean any inflammatory infliction, it does not mean that it is rheumatoid arthritis at all. But the fact that you have been having joint pain shows that it is very possible, and a family history could mean that it is genetic, but if it is controlled early, then you will not suffer joint damage because there will not be any scarring from not having it treated right away.

  2. Jo

    Will I get arthritis and is there anything I can do to prevent it?
    My mother has osteo and my father has rheumatoid. Is it genetic? Or is there anything I can do to keep it at bay or postpone the development of it?

  3. kkecs07

    Has anyone found a natural remedy for Rheumatoid Arthritis?
    I have had RA since I was 17 years old. It is a genetic form. I am responsive to Enbrel but not Plaquenil. Prednisone helps some. I am breastfeeding and have a low milk supply.My rheumatologist says that the reason that I am not making milk is due to my swelling from the illness. What are some natural ways to cure or stop the symptoms? Please no illegal drug references or immature answers. I am serious and expect the answerer to be too.

    1. keffer e

      especially don’t eat any of the” night shade family of foods.”look it up.
      nor any white flour products.”at all”.no sweets ,and red meat no fried foods.and DO take alfalfa tablets .3 with each meal.Its will better digest your food.and you will have better milk.and a good b vitamin fortify the t cells.and learn to relax.stress is very bad for r.a.take time every day a few times a day to just relax. OK?All This will improve your condition.I guarantee it.
      I wish you and your wonderful baby well.

  4. dolphindreams63

    what are the main symptoms of diabetes and rheumatoid arthritis?
    Both diseases run on my moms side of the family and,so far I have a few of those symptoms(according to my mom)

    but,I don’t know much.Like I have cuts and bruises,that never go away.Thats one thing.(I have to get a ganglion removed dec 5)although,my feet are also effected.

    So,symptoms of diabetes?
    symptoms of rheumatoid arthritis?(19 yrs old)

    1. ⓢⓒⓞⓣⓣⓢ ⓙⓡ

      There are basically two types of gene mutations in respect to disease. One type of mutation causes a disease. For example, the mutant gene may cause achrondroplasia (a form of dwarfism) or it may cause hemophilia or cystic fibrosis or sickle cell disease. The existence of genes that cause diseases has long been recognized.

      The other type of gene mutation does not directly cause a disease but rather predisposes to it. These genes make a person susceptible to developing a disease. These susceptibility genes often involve common chronic diseases such as diabetes and rheumatoid arthritis.

      An important finding has just been made about the genetic susceptibility to rheumatoid arthritis and autoimmunity. We will outline the finding.

      Background: Rheumatoid arthritis is the most common systemic autoimmune disease. It affects 1% of all adults in the world. The disease is characterized by immune-mediated destruction of the joint architecture. It is 2 to 3 times more common in women than men. The heritability of rheumatoid arthritis is 60%, reflecting a strong genetic component in the disease.

      Design of Research: To identify genes involved in the susceptibility to rheumatoid arthritis, a “discovery study” was done testing for 87 variations called SNPs (single-nucleotide polymorphisms) in candidate genes and regions. The discovery study involved 475 individuals with rheumatoid arthritis and 475 individually matched controls.

      Result: One of the SNPs was found to be associated with rheumatoid arthritis. It was a “missense” SNP in a gene encoding a protein tyrosine phosphorylase. This risk SNP was present in 28% of those with rheumatoid arthritis and 17% of the controls

      Comment: A variant of this same SNP encoding the same phosphorylase enzyme was recently found associated with type 1 diabetes, another autoimmune disease. It is beginning to look as if this variant phosphatase may increase the overall reactivity of the immune system and may raise the risk for autoimmune disease.

  5. a jaded angel

    Has anyone here moved to Arizona for arthritis relief?
    Hi. I was just wondering if living in AZ really does help with arthritis. Is it dry heat year round? Do you still need to take meds? Just curious. Thanks!

    1. gillianprowe

      If I had a cent for every time someone asked this question, I would not be answering it. I have known people who moved lock stock and kids to Arizona due to Arthritis. Fact, their is more Arthritis among the ‘Native’ people born and educated, in AZ than anywhere else in the world! So those people who are now 50 or 60, born in AZ, lived in AZ all their life have Arthritis, because of some genetic predisposition. Years ago I went to Las Vegas against my Doc advise? Now LV is in a Dessert, so by right the heat should really help with the Rheumatoid Arthritis and the Sun with the Psoriasis, what was the BIG problem? Umm air conditioning? The heat was too hot to maintain a normal, lets go for a nice 3 mile walk at 11am, in fact by 10am it was HOT. So while the Arthritis behaved itself, I started to cease up due to lack of exercise. By the time I got back to Europe, 10 days, the Psoriasis was cracking, splitting open and not nice. It had dried out along with my skin. The idea that AZ is good for Arthritis is a old wife tale. However I do know the local native population use tea made from some plant and sip it all day, as it eases the pain and inflammation. I think the longest anyone with Arthritis that I have known lived in AZ was 12 months, then they moved away, because it was too HOT! Just like some people prefer a hot pack for a strain, others will prefer a cold pack for a sprain.

  6. Daisy

    Can I still be a nurse if I have Rheumatoid Arthritis (RA) ?
    I just turned 18 and I was diagnosed with Rheumatoid Arthritis (RA)
    I’ve had it for a while just didn’t think it was possible for someone my age to get it so young it’s genetic in my family I got it early. Can I still perform the tasks of a nurse? Should I even bother going to college for it? Or should I pick a diffrent career

    1. ★☆✿❀

      Yes it’s definitely possible. I have a friend with Lupus who is studying to be a nurse.

      If you are under a rheumatologist, being treated and are prepared to study part time or at the pace you need to to keep your health and stress levels down, then yes.

      You might like to think about what you’d like to do when you’ve finished nursing. You’ll most likely find it difficult to be a surgical nurse for example. But I’m sure you know that rheumatology nurses aren’t on their feet a lot and spend time talking with patients. That might be more suitable.


  7. se

    I have a family history of rheumatoid arthritis. What are my chances of getting the disease?
    I have occasional joint pain in my left wrist and once it goes away, I wont have that pain for about 3-6 months. Should I got get checked out by the doctor to make sure it’s not RA?

    1. LloydTheFootMan

      My answer to this your last answer would be ‘yes’ go to the doctor and get tested. There are a few tests which can be done to determine if you are more at risk of developing RA.

      There is a genetic and heredity link with RA so it is possible you could develop RA, chances vary. For a more accurate questimation look back over your family tree and see if other people in the family had it and what percentage.

      With RA it is becoming more common practice to treat the condition early on, rather than waiting till its bad. This is meant to increase your functional outcome.

      I really suggest going to see your doctor, and these are all only my opinions.


  8. gloomgirl01

    Will I get Rheumatoid Arthritis if my mom has it?
    I’ve been having some aches on my knees around the same time my mother has them. My mom has had Rheumatoid Arthritis since her early 20s. I’m in my early 20’s now and would I get Rheumatoid Arthritis if she does?

    1. Rita S

      I have Rheumatoid Arthritis and my daughter has the same fear. A lab test called RA factor could tell if you could possibly have it. Normal is 0-20. Mine is 217. The reason I mention to have it checked is because my son has multiple sclerosis which is an auto-immune disease, and so is RA. Coincidence? I doubt it. I do believe it is genetic. Good luck and get it checked.

  9. Marisa

    Is color blindness reversible if it is caused by certain medications?
    My dad is taking methotrexate, folic acid, plaquenil, and prednisone for his rheumatoid arthritis. He is beginning to go color blind. He works in the automotive industry and one of the things he does is mix paints for cars so this is an obvious setback. I want to know if it is reversible if caught early enough.

    1. Adam

      Plaquenil and methotrexate both do funny things, vision-wise. Generally non-genetic colour vision deficiencies are reversible, but he may not be able to go off the medications either. He should specifically ask the eye doctor for a colour vision test using caps (Farnsworth D-15 is the typical one, although there’s a 100-hue version specifically for people who work with colours for their jobs), to pick things up as early as possible.

    1. ★☆✿❀

      Basically, Gout is caused by increased levels of urine acid in the blood which crystallized and deposited in joints, tendons and other tissues. It usually affects the big toe but other joints can be involved. There are thought to be two main causes of gout, there seems to be some sort of genetic link. Not everyone with a family history of gout with get it. The other is lifestyle, diet has been linked to gout more so than many other conditions. There’s a strong link between foods such as alcohol, sugary drinks, meat and seafood and the development of gout. Gout usually affects men over 30 and woman over 50 and particularly those of American American or Pacific decent.

      Rheumatoid arthritis is a dysfunction of the immune system, as it is an autoimmune disease. This means that the immune system believes that it’s own tissue is a foreign body and begins to attack it. Any joint can be affects, but usually the hands, feet and wrists. Because it’s an autoimmune disease, it is seen more commonly in individuals with a family history of other autoimmune diseases (i.e. Celiac Disease, Hashimoto’s, Crohn’s Disease). There also seems to be an environmental trigger that sets off the immune system. In many cases this is never identified. Usually treatment involves slowing down the disease by suppressing the immune system. It usually affects woman between the ages of 20-50, but can affect children and men.

      They do have many of the same symptoms, but the pathology behind the conditions is very different.


  10. PeaceOutCyclist

    What type of disease is Rheumatoid arthritis?
    I know it’s chronic, but I have to choose: genetic, nutritional, bacterial, viral, fungal, or teratogenic.
    Thanks 🙂

    1. natpractitioner

      None of the above. It is more correctly described as an autoimmune disorder. However, it is not so simple.

      There is a genetic component to it, but this is not the only cause. There is a nutritional component to treatment [as there is with everything] as well. It is not bacterial or viral, though there is a theory that says that some type of bacteria or virus may trigger the immune response that causes the body to turn agaisnt itself.

  11. WarGD3

    genetic predisposition in the development of rheumatoid arthritis?
    can someone please explain the genetic predisposition in the development of rheumatoid arthritis
    Anyone knows how the genes can result in RA?

  12. bailey

    Can someone please tell me if this info is correct?
    Genetic Disease
    Rheumatoid Arthritis, or RA, is a condition that affects the joints causing inflammation and pain. Several determinants influence the vulnerability to RA. Rheumatoid arthritis is described to have autoimmune factors as well as genetic factors. An autoimmune disease is an illness involving body tissues being assailed by an individual’s immune system. This involves RA and it can, although not completely proven, run in families. In attempts to find the main source of this disease, scientists have conducted studies and found some enlightening facts, but they can be confusing.
    Other causes of RA can be environment or habits of the individual. Although men seem to carry the gene, women have it more often. Children can get it, but it usually occurs at an older age where the joints have weakened and are more susceptible to arthritis. Symptoms include the inflammation and extreme pain in joints. Those with RA may find it difficult to move.
    Whether or not RA is autosomal or sex-linked is a tough question. Autosomal means that it is not carried by chromosomes X and Y. But studies have shown that probands for RA, or a person with a disorder who is the first to be a subject in the study, have shown that gender is a more important factor than age in the onset of rheumatoid arthritis. Overall, gender is the determinant of risk for RA, and male probands have the greatest risk in carrying the mutant gene that may be the cause for RA. The first studies in regards of rheumatoid arthritis being a genetic disease were done in 1994. This study suggested that families with an excess of affected males at a young age might be the most informative in identifying the “considered” recessive gene.The cause for rheumatoid arthritis is referred to as a highly recessive gene with “mutant allele frequencies,” an allele that differs from the “standard” allele.The exact location of Ra is 16p13.1q22.1p13.6qz3.6p21.3.6pz1.3.5q31.2q32.2-q32.3.1p36.13.1q31-q32. Since RA is recessive, it must have two copies of that mutant allele in order for it to be expressed.Other studies based on first degree parents, family members who share fifty percent of their genes with another particular individual, the physical characteristics, or phenotype, can be linked to a recessive major gene. A major gene is is any gene individually associated with distinct physical affects. This is the most controlled explanation to the cause of RA in regard to genetics.

    1. Jahansha

      Genetic Background-Conditioned Results

      We used a collection of 749 SNPs informative for European substructure to stratify both the cases and controls in Sample Set 2 [41]. By partitioning cases and controls into similar genetic background groups (“Northern European” or “Other”), our aim was to interrogate the data for strata-specific effects – that is, whether or not association signals were specific to one of these genetic background groups – and avoid potential confounding by population stratification. Although two SNPs demonstrated moderately higher significance levels following stratification – rs16910233 in C5 (PNorth = 0.019 compared to PUnstrat = 0.147) and rs12685539 in CEP110 (POther = 0.038 compared to PUnstrat = 0.115), a Breslow-Day test of effect heterogeneity comparing ORNorth and OROther was not significant. Furthermore, a positional plot of Mantel-Haenszel P-values, testing for association given the genetic background stratification, was very similar to the unadjusted plot (Figure S1) suggesting that stratification of the case and control samples by SNPs informative for European substructure did not change the association patterns in Sample Set 2.

  13. Monty Noblezada

    Will I inherit arthritis if both my parents have it?
    Just curious, my parents don’t have severe cases of it though. Is arthritis caused by the nature of their work or is hereditary? They both do the same thing every day at work.

    1. ★☆✿❀

      If your parents have osteoarthritis then there’s no genetic link. Nearly everyone will develop osteoarthritis eventually. It’s caused by wear and tear of the joints. So you should make sure you look after your joints. You have an increased risk of developing osteoarthritis if you have a physically demanding job, or if you play a physically demanding sport and have repetitive injuries.

      But if your parents have Rheumatoid Arthritis, Lupus, Psoriatic Arthritis, Ankylosing Spondylitis or any other autoimmune arthritis, the YES you do have an increase risk. Having one autoimmune disease in your family makes you more likely to develop one. So if your Mum has an autoimmune thyroid problem, then you’re more at risk of developing Rheumatoid Arthritis, albeit, not by much. Although Claudia (the other answer) says that autoimmune diseases are not genetic, she is wrong. All my specialists (rheumatologist, ophthalmologists, oral diagnostic specialists and my GP) all have asked me time and time again about autoimmune diseases in my family.

      You should do your best to avoid over use of your joints, take Omega 3 supplements and don’t smoke. Cigarette smoking has been found to dramatically increase your chances of developing Rheumatoid Arthritis.

      Good luck.


  14. 45757

    Why is it that two brothers can vary in height by up to three inches?
    I know someone who is 5″8 and his brother is 5’9

    I also know another set of brothers, the oldest is 5’9 and the younger is about 6’0.

    Now why is this? Usually height is predicted based on both your patents heights? I happen to have stopped growing at 5’7, the exact same height as my father, and never grew another inch.

    So what does this mean if two brothers so often are several inches away from each other? Does it mean that height depends on more than genetics? Can you inherit a genetic for height that is not displayed by either of your parents?

    1. greydoc6

      Mean parental height is only a statistical indication of an individual’s final height. The most important factor is the roll of the genetic dice when that particular sperm penetrated that particular ovum.

      Nutrition plays a role, too. The average American young male is almost two inches taller than his grandfather was when he fought in WWII. Same in Japan. This is assumed to be due to improved availability of food.

      Illness and disease in childhood may play a role, too. Classic example would be juvenile rheumatoid arthritis, especially if high doses of steroids were used for treatment.

      Finally, there are genetic diseases associated with short stature, but I don’t think this is what you were referring to.

  15. Monica

    Any good Rheumatologist in New Jersey, I hv sever Rheumatoid arthritis, need to visit a doc!!?
    Hello all,
    I have been suffering from Rheumatoid arthritis of the spine, namely ankylosing spondylitis. I need help urgently, kindly guide me to a very good doctor, who has very good reviews, and is very well known in the New Jersey area!!

    1. Genius

      ankylosing spondylitis is much more common in male, and is genetic, you might have the hla b27 factor. you have a bamboo spine for that matter and experience severe stiffening and back pain. you simply need steroids to combat such as there is no definite treatment for this autoimmune disorder, I am not from new jersey, sorry

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