Lupus Anticoagulant Miscarriage Symptoms

Question: How Does Heparin Help Treat Recurrent Miscarriagesc

Heparin is an injectable blood thinner. Doctors sometimes prescribe heparin to women with antiphospholipid syndrome or other blood-clotting disorders that are linked to recurrent pregnancy loss.


Recurrent miscarriages occur due to a number of causes. Some causes are more well understood than others, and in many cases, there is no known cause for recurrent miscarriages. One of the few medical factors doctors agree upon in recurrent miscarriages is thrombophilia disorders, or medical conditions in which the blood has an increased tendency to clot. The thrombophilia disorder most clearly tied to miscarriages is antiphospholipid syndrome.

In thrombophilia disorders, researchers believe that tiny clots get stuck in the developing placenta, blocking flow of nutrients to the baby and eventually causing miscarriage (or increasing risk of other pregnancy complications, such as pre-eclampsia). It’s also been theorized that thrombophilia disorders might cause other problems with the placenta.

For women with diagnosed thrombophilia conditions and recurrent miscarriages, a common treatment is heparin — often alongside low-dose “baby” aspirin. Heparin injections thin the blood and decreases the tendency to form clots. Evidence suggests that heparin treatment during pregnancy reduces miscarriage rates for women with antiphospholipid syndrome and possibly benefits women with inherited thrombophilia disorders, such as Factor V Leiden mutations.

Using heparin during pregnancy is not without risk; the drug can have side effects in some people and may increase the risk of bone loss or tendency to hemorrhage. But for women with antiphospholipid syndrome, the benefits likely outweigh the risks.

Some experts had theorized that heparin might be beneficial for women with recurrent miscarriages and negative tests for antiphospholipid antibodies, postulating that unexplained recurrent miscarriages could be due to some unrecognized blood clotting disorder, but a 2010 study found that neither heparin nor low-dose aspirin improved birth rates for these women compared to placebo. Heparin treatment is usually recommended only in women with both a history of miscarriage and a confirmed diagnosis of antiphospholipid syndrome or an inherited thrombophilia disorder.

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Before we proceed to miscarriage signs, let’s understand the causes of miscarriage. Miscarriage usually happens in the first trimester (12 weeks) of pregnancy with more than 90% of miscarriages happen within the first 8 weeks of pregnancy. It affects 10% to 20% of all confirmed pregnancies. Though most people believe it is a natural causes, experts have identified several known causes of miscarriage. They are:

1. Genetic factors and hormonal imbalances which affects the quality of the chromosomes, or the quality of the egg
2. The age of the mother-to-be (those who are over 35 have high tendencies)
3. Dependency on certain drugs or treatment such as dependency on insulin by diabetic patient.
4. Certain infections like Chlamydia or certain viruses
5. Systematic disorders, for instance lupus
6. The kind of lifestyles such as the level of alcohol, drugs or smoking consumption taken constantly.

So how do you know that you are having a miscarriage? Let’s identify the well-known miscarriage signs.

1. Having an abnormal vaginal bleeding just like a heavy period, this usually happen within the 6 weeks of pregnancy.
2. Having a cramp pelvic and back pain which increases from a mild pain to a severe pain as well as bleeding. The bleeding of fragment of tissue may occur as well. Normally the pain is worse than your usual menstrual period pain. This situation usually happens between 6 to 12 weeks of pregnancy.
3. Having an open cervix as well as bleeding and pain just like during the labor – this usually happen after the first trimester.

A sudden stop of pregnancy symptoms like nausea or morning sickness may not be the best indicator of miscarriage. This is because some mother-to-be will have these symptoms gradually disappear when they proceed into the second trimester.

If you have any of the above mentioned of miscarriages signs, the very first action you have to do is to consult your doctor. The doctor will perform some test like pelvic examination, blood test to determine HCG levels and the ultrasound test. From these test, a confirmation can be made.

Miscarriage leads to depression and grief. Spend more time with close friends and family members who care about you and give moral support to you. Always think positive and there is always be joy during pregnancy. There is nothing wrong if you want to cry as much as you want. That will help you to release such a big emotional burden out of you. Last but not least, always pray to strengthen your emotion, to be given a healthy body and no more miscarriage signs in the future.