systemic lupus erythematosus mayo clinic

8 thoughts on “Systemic Lupus Erythematosus Mayo Clinic

  1. xoxo_peridot05_xoxo

    Can my dog get lupus disease if he was near a dog who had it? …is it contagious?
    i was walking my dog (spaniel) and we saw this dog coming towards us who had lupus…i didnt want to be rude to the owner so i let them sniff each other…will my dog get affected???
    PLS!!! help
    FYI to ppl who said how can i detect if the dog had lupus….

    THE owner told me and you can see his face was hairless….

    1. Yogi and Me

      i think that’s genetic not a contagious disease. You can’t get Lupus from someone who have them either.
      here’s the definition from Mayo clinic
      Lupus is a chronic inflammatory disease that occurs when your body’s immune system attacks your own tissues and organs. Inflammation caused by lupus can affect many different body systems, including your joints, skin, kidneys, blood cells, heart and lungs.

      Lupus occurs more frequently in women than it does in men, though it isn’t clear why. Four types of lupus exist — systemic lupus erythematosus, discoid lupus erythematosus, drug-induced lupus erythematosus and neonatal lupus. Of these, systemic lupus erythematosus is the most common and serious form of lupus.

      The outlook for people with lupus was once grim, but diagnosis and treatment of lupus has improved considerably. With treatment, most people with lupus can lead active lives.

  2. Saoirse

    Diseases that will eventually kill you? Help!?
    So, I’m writing a book where the main character has Lupus, and I’d like to learn more about it. So if any one of you could tell me a bit what it’s like, how it occurs, how it’s discovered, how it’s treated.

    I know I can google it and stuff, but it’s explained in such complicated ways. Help?

    – Is it discovered at once when you’re born or could it take some time? Say, years? And if so, when it hits, how does it hit?

    1. ★☆✿❀

      Lupus is an autoimmune disease. This means that the immune system attacks itself instead of attacking infections and viruses. The type you’re talking about is Systemic Lupus Erythematosus (SLE)

      The most common symptoms are fatigue, joint pain/swelling, rashes, kidney problems and mouth and nose ulcers. It can also cause seizures, dry eyes and mouth, sun sensitivity, fevers, inflammation of the heart and lungs, chest pain, hair loss, stomach pain,

      People with Lupus usually experience symptoms for a period (flare ups) and then have periods of fewer symptoms or no symptoms (remission).

      It can take years to discover, I think it’s about 6-7 years on average. The first blood test that’s used is called the ANA test or Anti-Nucleic Anti-Body. It’s positive in about 93-98% of people with Lupus (but it’s also found in other autoimmune diseases and healthy people). If this test is positive then there are other tests that’d be ordered. The most commonly positive test in people with Lupus is the Anti-dsDNA. People with Lupus sometimes have a Vitamin D or Iron deficiency. There are other blood tests that are ordered and if you’d like more information on them, just let me know.

      Doctors also order tests to check the function of your liver and kidneys. Kidneys are more commonly involved than liver and they often excrete protein.

      There are other forms of Lupus that affect just the skin. Some that are induced by drugs. Some that are found in new borns. Systemic Lupus usually begins between 10-50 years old. Doctors think it’s hormonally triggered. Some people experience symptoms slowly, other experience then over night.

      People with Lupus very rarely die these days. The medication available has improved so much, has does testing. The most common cause of death is from infection caused by a weakened immune system from the medication or from organ involvement.

      The medications that’s are usually used to treat Lupus are Plaquenil and Prednisone. Plaquenil was used to treat Malaria, but it was found to be helpful in Lupus, Sjogren’s and Rheumatoid Arthritis. It can cause eye damage, but doesn’t suppress the immune system. Prednisone is a steroid and can cause a number of side effects. Doctors don’t like you to be on it long term, but in some people it’s necessary. In those with a more serious disease Methotrexate, Imuran and Cellcept are used. These suppress the immune system and are often used in people with organ involvement.

      The Mayo Clinic website is really helpful. It’s pretty simple and they don’t over complicate things. Lupus is a tricky disease and can mimic other conditions like Rheumatoid Arthritis and Multiple Sclerosis.

      I hope that’s been helpful.


    1. rr

      From the Mayo Clinic:
      DHEA (dehydroepiandrosterone) is an endogenous hormone (made in the human body), and secreted by the adrenal gland. DHEA serves as precursor to male and female sex hormones (androgens and estrogens). DHEA levels in the body begin to decrease after age 30, and are reported to be low in some people with anorexia, end-stage kidney disease, type 2 diabetes (non-insulin dependent diabetes), AIDS, adrenal insufficiency, and in the critically ill. DHEA levels may also be depleted by a number of drugs, including insulin, corticosteroids, opiates, and danazol.

      There is sufficient evidence supporting the use of DHEA in the treatment of adrenal insufficiency, depression, induction of labor, and systemic lupus erythematosus.

      No studies on the long-term effects of DHEA have been conducted. DHEA can cause higher than normal levels of androgens and estrogens in the body, and theoretically may increase the risk of prostate, breast, ovarian, and other hormone-sensitive cancers. Therefore, it is not recommended for regular use without supervision by a licensed health professional.

      And this from another site:
      Despite being a hormone precursor to testosterone it is unclear that DHEA would even work when taken orally. Most anabolic (muscle building) hormones must be injected because they are inactivated during digestion. Oral anabolic hormones must be chemically processed to resist inactivation in the digestive system. It is known that long term use of oral anabolic steroids is associated with increased risk of liver cancer and other medical problems.

  3. Anonymous

    Need help for my biology assignment?
    A 45 year old man came to the emergency department complaining about shortness of breath, chest pain which is came to the emergency department complaining about shortness of breath, chest pain which is severe by deep breathing of one week duration. he had generalize easy fatigability, malaise,skin rash that worsens with sun exposure, fever and joint pain for about three weeks prior to his current complaint. Physical examination revealed the following:
    General appearance: Acutely sick looking, in sever cardiorespiratory distress
    Respiratory rate 32 , Heart rate 112, Blood pressure 110/68, Temperature 37.8 C
    He has erythematous malar rash, decreased air entry on both sides of the lung, there is pericardial friction rub on the pericardium.
    The knee and wrist joints are swollen and painful.

    The attending physician ordered the following lab tests with the impression of Systemic lupus erythematosus.
    White blood count elevated, ESR (Sedimentation Rate) very elevated, Xray bilateral pleaural and mild pericardial effusion
    ANA and Anti Ds antibody positive.
    Then the patient was started with high dose prednisolone by the intravenous route and responded well to treatment after a couple of weeks.

    .What are the organ systems affected in this patient
    do you think the prednisolone helped the patient?
    What is the pathophysiology behind this illness?

    1. Anonymous

      Lupus is an autoimmune disease. Autoimmune diseases are when a persons own immune system messes up and doesn’t recognize part of the patients body and then attacks it as if it were an invader. This means, that the pathophysiology is that antibodies are created against the part of the patients own body. Normally, (normal physiology) antibodies are only created to recognize intruders, like viruses and bacteria. In systemic lupus erythematosus, the immune system generates antibodies against connective tissue, which is the stuff that holds your body together, like collagen, and cartilage.

      Prednisone should help the patient because it is a corticosteroid, which are drugs that regulate the immune system to reduce inflammation.

      If you want to read more, check out the Mayo Clinic’s website. It is a great resource for easy to understand info.

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