Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a cystic genetic disorder of the kidneys.There are two types of PKD: autosomal dominant polycystic kidney disease (ADPKD) and the less-common autosomal recessive polycystic kidney disease (ARPKD).
It occurs in humans and some other animals. PKD is characterized by the presence of multiple cysts (hence, “polycystic”) typically in both kidneys; however 17% of cases initially present with observable disease in one kidney, with most cases progressing to bilateral disease in adulthood. The cysts are numerous and are fluid-filled, resulting in massive enlargement of the kidneys. The disease can also damage the liver, pancreas and, in some rare cases, the heart and brain. The two major forms of polycystic kidney disease are distinguished by their patterns of inheritance.Polycystic Kidney Disease is an inherited kidney disease. The main problems are symptoms of PKD, rupture of cysts, complications of Polycystic Kidney Disease including kidney failure, high blood pressure, etc.
Symptoms of PKD
Symptoms of different severity like hypertension, nausea and vomiting appear after renal insufficiency come into being.
If a cyst ruptures, the cyst is easy to be infected, and then more symptoms such as frequent urination, high fever, persistent bleeding could present. In rare cases, there are serious signs of ruptured kidney cysts.
Kidney failure is a prominent hazard of PKD, while those symptoms are indicators showing that the patients are suffering from PKD. Usually patients with PKD are careless of their disease in early stage because almost no symptom can be identified. They become aware of the hazards of PKD only after their disease develops into kidney failure. At this point, toxins can't be expelled as usual and are accumulated within the human body, leading to severe symptoms for patients who then need dialysis.
So sufferers with PKD should notice health care in daily life, learning hazards of PKD as early as possible and take care of their daily diet. Then the occurrence of kidney failure which is caused by PKD can be avoided to the hilt.
By comparison, the situation is totally different for Polycystic Kidney Disease. Some people with PKD can live a normal life without knowing he or she has this disease. Kidney functional cells may be damaged as cysts expand. Eventually Chronic End-stage Renal Failure or Uremia comes into being.
Hence be confident that your Polycystic Kidney Disease developing can be prevented effectively.