Diabetic Nephropathy is a complication that occurs in some people with diabetes.diabetic nephropathy is characterized by a progressive increase in proteinuria and decline in GFR, hypertension, and a high risk of cardiovascular morbidity and mortality.
1. Proteinuria( protein in urine)
It is the first sign of Diabetes of Kidney Disease. The glomerular filtration rate (GFR) starts to decline when persistent proteinuria occurs. The amount of proteinuria will increase gradually with the progress of illness condition. When the GFR declines to a level lower than the normal range and the large mass of proteinuria presents, Diabetic Kidney Disease can develop into Kidney Failure rapidly.
About half of patients with Diabetes of Kidney Disease will present swelling. Because the mass loss of proteins, plasma oncotic pressure (plasma colloid is mainly composed of plasma protein) will reduce. As a result, the water retention in the tissue space will lead to swelling.
3. High blood pressure( Hypertension)
Most patients with Diabetic Kidney Disease will present high blood pressure after presenting proteinuria for a long time, which is often the late stage of Diabetes of Kidney Disease. What is more, the occurrence of high blood pressure speeds up the aggravation of Diabetes of Kidney Disease. So, patients should keep their blood pressure under control.
Diabetes of Kidney Disease patients who have azotemia will present light to moderate anemia, which will not improve with treatment of chalybeate. It usually occurs when the GFR is 45 lower.
5. Renal insufficiency
The GFR will increase to discharge sugar; the urea nitrogen and serum creatinine are in the normal level at the early stage. However, when persistent proteinuria occurs, there will be an increase of urea nitrogen and serum creatinine, thus causing Renal Insufficiency. If this condition continues for a long time, end stage renal failure (ESRD) will occur.
Besides the above signs and symptoms of Diabetes of Kidney Disease, retinopathy can also occur although it does not belong to the symptoms of kidney diseases. Once the above signs and symptoms occur, patients should take further examinations so that the condition can be improved to the largest extent.
The improvement after Stem Cell Transplant for patients with Diabetic Nephropathy: After the treatment of Stem Cell Transplant, the symptoms of 'drinking more, eating more, urine more and weight loss' will be greatly improved or disappeared. The Complications such as Hypertension, Hyperlipidemia and kidney and nervous system damage will be improved and recovered. The whole treatment is safe and with little side effect. Many clinical cases proved that after Stem Cell Transplant, the patients can reduce glucose-lowering medicine and insulin. If the patients insist the treatment, the disease condition will turn better. We hope the patients can receive Stem Cell Transplant early. Stem Cell Transplant can surely be used to treat Diabetic Nephropathy. The above is the introduction of Stem Cell Transplant. If you have any problems, please write email to firstname.lastname@example.org