Chronic lymphocytic thyroiditis or autoimmune thyroiditis is one of the most common thyroid diseases. It affects 10-12% of the population. Female domination is net, ratio women / men is 9/1 in one of the most common clinical manifestations of this disease, so-called Hashimoto's

Autoimmune thyroiditis encompasses several entities: the form of goitre (Hashimoto's thyroiditis have mentioned above), lymphocytic thyroiditis of child and adolescent, called atrophic thyroiditis, the quiet (no special clinical manifestations found by usually on the occasion of thyroid exploration), post partum thyroiditis (encountered in 2-7% of pregnant women), focal thyroiditis (localized only in the thyroid area).

Thyroiditis is often associated with other autoimmune diseases with the same autoimmune pathogenesis: diabetes mellitus, adrenal insufficiency, pituitary, hypo parathyroid, vitiligo, Biermer anemia, lupus, rheumatoid arthritis, dermatomyositis, polymyositis, myasthenia, etc.

Silent thyroiditis may have an autoimmune origin. It is associated with transient release of thyroid hormone excess and low radio-iodine caption. It may meet both in women (not related to pregnancy), and men. Hypothyroidism is not permanent. Autoimmune thyroiditis, especially Hashimoto thyroiditis is more common in people with various autoimmune diseases.

Pathogenic factors in autoimmune thyroiditis are genetic predisposition, combined with specific triggers. Cell-mediated autoimmunity, humoral autoimmunity and genetic predisposition play a role in autoimmune thyroiditis. Genetic predisposition along with environmental factors is required for activation of the autoimmune process. Autoimmune thyroiditis is more common in women than in men because of genetic and hormonal factors. Diet high in iodine has a clear role. Smoking increases the risk of hypothyroidism in Hashimoto's thyroiditis and the risk of ophthalmopathy in Grave's disease. Stress can also have a role in autoimmune thyroiditis. Various cytokines are involved in the development of autoimmune thyroiditis. Interferon-a, IL-2, colony stimulating factor by macrophages can induce autoimmune thyroiditis.

Autoimmune thyroiditis and reproductive function

Thyroid hormones play an important role in reproductive function, both through direct effects on the ovaries and indirectly through interactions with sex hormones (estradiol, progesterone). There's long known the effect of hypothyroidism on the female reproductive system. These patients may experience oligomenorrhea, menometroragy, and anovulatory menstrual cycles. Furthermore, patients with untreated hypothyroidism have a high rate of failure in obtaining pregnancy even using methods of assisted reproduction (IVF). This group of patients is still only the tip of the iceberg. Numerous studies have shown a strong association between the presence of autoimmune thyroiditis in patients with normal thyroid function and disease generating infertility (endometriosis, ovarian micro polycystic syndrome, primary ovarian failure) and an increased rate of recurrent spontaneous abortions. Significant efforts have been made to find a way to prevent miscarriage in patients with autoimmune thyroiditis. The best results were obtained after administration of levothyroxine (euthyrox) – even for the group of patients with normal thyroid function and autoimmune thyroiditis.

The cause of hypothyroidism during pregnancy is autoimmune thyroiditis. Many patients with autoimmune thyroiditis develop during pregnancy a state of hypothyroidism (insufficient thyroid function) from a state of normal thyroid function. Thus hypothyroidism may develop or worsen during pregnancy. Pregnant patients with hypothyroidism are at increased risk of miscarriage, anemia, gestational hypertension, placental abruption, preterm delivery, postpartum hemorrhage. Beyond obstetrical complications, deficit of thyroid hormones in the mother may affect fetal development. Multiple studies have shown an association between maternal hypothyroidism and inadequate child neuro development. Prompt treatment with levothyroxine (euthyrox) reduces the risk of these complications to both mother and child.

Natural treatment for autoimmune thyroid with Calivita products

– Evening Primrose Oil late the complications of diabetes, has positive influence on the thyroid function and reduce the aging process.

– The immune system can be enhanced with nutritional supplement ImmunAid by supporting normal immune function and helping maintain the resistance.

– The balance between immune and hormonal system can be maintained with nutritional supplement Rhodiolin that can prevent and treat autoimmune diseases, due to the quality to improve the function of thymus gland.

– Noni Liquid support the immune system, contribute to the formation of antibodies and also blocks the growth of viruses. It is beneficial in treating a variety of diseases, from the simplest to most complex.

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lupus autoimmune diseases in children

23 thoughts on “Lupus Autoimmune Diseases In Children

  1. celticgirl

    What is an interesting in-service topic idea for pediatric physical therapy?
    I need some ideas for something that could be fun, educational, and interactive??

    1. Mary

      Here is the list we made for our SPT and SPTA for ideas. Hope it helps. I work with school age kids in a public school

      In-service ideas
      1.Alternative therapies _______
      2.Update in treatment of_______
      3.Ehler Danlos Syndrome
      4.Teens and strokes
      5.Evidence based home exercise programs/compliance/things to aid in compliance
      6.Fitness/update in exercise protocols for kids
      7.Treatment of vestibular problems in children (dizzy—work of Gayle Cronin??)
      8.Hyperbaric oxygen
      9.Update in muscular dystrophies
      10.Review of _____
      11.ABA vs. floor time
      12.Dwarfism-varies types-acrondroplasia, Diastrophic Dysplasia,
      13.Use of rollers, sit fit, bosu in therapy
      14.CHARGE Syndrome
      15.Noonan Syndrome
      16.Tuberous Sclerosis
      17.DiGeorge Syndrome
      18.Pediatric Lupus
      20.Possible comorbities of Down Syndrome –Leukemia, dementia, sleep apnea, hypothyroidism, cardiac problems etc. 21.Metabolic disorders in children
      22.Charcot-Marie-Tooth disease
      23.Hypoplastic left heart syndrome
      24.Neuromobilization in children
      25.Pilates for kids
      27.Review of pediatric outcome measures
      28.Differential diagnosis of ______________
      29. Headaches in children
      30.Treatment ideas to improve poor posture in kids
      31.Pediatric autoimmune diseases
      32.Update on HIV in children
      33.Interesting case study including treatment ideas, home programs etc
      34.Caudal regression sequence
      35.Differential diagnosis/ Review of foot deformities (diff diagnosis) partial syndactyly, meta adductus, pes planus, pronation etc.

      Ones done recently by our studentststudents in
      EBM of SI,
      idiopathic scoliosis update
      Wii rehab
      Larson Syndrome
      Plyometrics for kids,
      Treatment for DCD
      ball exercise and case study
      obesity in children, CASE study with HEP
      OI, SMA

  2. superchick2314

    Is there a connection between lupus and cysts?
    I had two different cysts that had to removed as a child. One from my knee when I was four and one from my chest when I was seven.

  3. Rachel

    What does it mean to have a low platelet count?
    My friend’s brother went to the hospital today, and has as low platelet count (his count is 9000). I red on WebMD that a normal count for a child (he’s five) is from 150,000-450,000. Can anyone tell me what might be wrong and whether or not he’ll be okay? Thanks so much!

  4. Ian

    What exactly does a rheumatologist do?
    In the every day life of a rheumatologist, how would one treat patients, use technology for treatment etc? Is surgery involved?

    1. sunraytannedup

      rheumatologist is an internist or pediatrician who is qualified by additional training and experience in the diagnosis and treatment of arthritis and other diseases of the joints, muscles and bones. Many rheumatologists conduct research to determine the cause and better treatments for these disabling and sometimes fatal diseases.

      What kind of training do rheumatologists have?

      After four years of medical school and three years of training in either internal medicine or pediatrics, rheumatologists devote an additional two to three years in specialized rheumatology training. Most rheumatologists who plan to treat patients choose to become board certified. Upon completion of their training, they must pass a rigorous exam conducted by the American Board of Internal Medicine to become certified.A rheumatologist is a clinician specialized in the field of medical sub-specialty called rheumatology, and holds either a Doctor of Medicine Degree (M.D.) or a Doctor of Osteopathic Medicine degree (D.O.). Training in this field requires four years undergraduate school, four years of medical school, and then, in the United States, three years of residency, followed by two or three years additional Fellowship training. The number of years allocated for specialized training in rheumatology for postgraduate trainees in different countries could vary according to the requirements of different countries. Rheumatologists are internists, physicians or pediatricians who are qualified by additional postgraduate training and experience in the diagnosis and treatment of arthritis and other diseases of the joints, muscles and bones. Many rheumatologists also conduct research to determine the cause and better treatments for these disabling and sometimes fatal diseases. Treatment modalities are based on scientific research, currently, practice of rheumatology is largely evidence based. Clinicians who specialize on this specialty are called Rheumatologists.

      What do rheumatologists treat?

      Rheumatologists treat arthritis, certain autoimmune diseases, musculoskeletal pain disorders and osteoporosis. There are more than 100 types of these diseases, including rheumatoid arthritis, osteoarthritis, gout, lupus, back pain, osteoporosis, fibromyalgia and tendonitis. Some of these are very serious diseases that can be difficult to diagnose and treat.
      Diseases diagnosed or managed by the rheumatologist include:

      Rheumatoid arthritis,Lupus, Sjögren’s syndrome, scleroderma (systemic sclerosis),dermatomyositis,polychondritis, polymyositis,polymyalgia rheumatica, osteoarthritis, septic arthritis, sarcoidosis
      gout, pseudogout
      ankylosing spondylitis
      reactive arthritis (aka **reactive arthropathy)
      psoriatic arthropathy
      enteropathic spondylitis
      polyarteritis nodosa
      Henoch-Schönlein purpura
      serum sickness
      Wegener’s granulomatosis
      giant cell arteritis
      temporal arteritis
      Takayasu’s arteritis
      Behçet’s syndrome
      Kawasaki’s disease (mucocutaneous lymph node syndrome)
      Buerger’s disease (thromboangiitis obliterans)
      Juvenile Idiopathic Arthritis(JIA) ;

      ( JIA inccudes a wide range Joint Disoders affecting Children)

      Rheumatic arthritis;

      Soft Tissue Rheumatism; ( Localizes diseases and lesions affecting the joints and structures around the joints including tendons ,ligaments capsules, bursae, Stress Fractures, muscles , nerve entrapment, vascular lesions , ganglion, connective tissue abnormalities and localised Soft tissues disorders etc.)
      Diseases affecting bones;
      Osteoporosis, osteomalasia, renal osteodystrophy, Fluorosis, Rickets Etc.
      Congenital and familial Disorders affecting Joints;
      Hyperextensible joints;
      Ehlers-Danlos Syndrome,Achondroplasisa, Marfan’s Syndrome etc

      When should you see a rheumatologist?

      If musculoskeletal pains are not severe or disabling and last just a few days, it makes sense to give the problem a reasonable chance to be resolved. But sometimes, pain in the joints, muscles or bones is severe or persists for more than a few days. At that point, you should see your physician.

      Many types of rheumatic diseases are not easily identified in the early stages. Rheumatologists are specially trained to do the detective work necessary to discover the cause of swelling and pain. It’s important to determine a correct diagnosis early so that appropriate treatment can begin early. Some musculoskeletal disorders respond best to treatment in the early stages of the disease.

      Because some rheumatic diseases are complex, one visit to a rheumatologist may not be enough to determine a diagnosis and course of treatment. These diseases often change or evolve over time. Rheumatologists work closely with patients to identify the problem and design an individualized treatment program.


      Apart from an extensive medical history, there are useful methods of diagnosis both performed easy enough in a physical examination and, on the other hand, more complicated ones,

    1. NJ

      No. Lupus is a autoimmune deficiency and blood can not be donated. It is not contagious but has some of the same symptoms as HIV which is contagious. On my drivers license it shows I’m a donor, if anything can be used I’m sure the doctors will make that decision, but in all honesty I do think we can be a donor.

      HIV is a choice with Lupus you are dealt the hand to bear this consuming disease.

  5. star2me80

    Has anyone been diagnosed with Antiphospholipid Syndrome? How did you find out, did you have any miscarriages?
    Thinking this might be going on with me, Doctor said from last miscarriage this could of been the problem. Both previous miscarriages were at 14-15 weeks, I do have other children before these miscarriages, and I am pregnant now and taking an aspirin a day as instructed by my doctor…thanks!

    1. Starcatcher

      I’m sorry for your losses. I also lost a baby at 15 weeks. Test showed she was normal so they suspect the issues were with the placenta. I’m in the 2ww (1 day to go) but have already been taking a daily baby aspirin for the past week.
      Diagnoses is done by a antiphospholipid antibodies blood test. Sometimes they will also run a PT/PTT blood test which times how fast your blood clots.
      It’s an autoimmune disorder which can cause abnormal clotting (thrombosis) of arteries (stroke, infarction) and/or veins (phlebitis), premature miscarriages (spontaneous abortions), abnormally low blood platelet counts (thrombocytopenia), purplish mottling discoloration of the skin (livedo reticularis), migraine headaches, and a rare form of inflammation of the nervous tissue of the brain or spinal cord, called transverse myelitis. Antiphospholipid antibodies have also been detected in over half of patients with the immune disease systemic lupus erythematosus.

  6. 터커 hσnєstlч

    is it possible to be born with the inability to reproduce?
    if a person is born (female) with the inability to reproduce? if her girl parts just didnt function but she has them?

    is this possible? what is it called? or is there a syndrome like that?
    because i think i was born that way
    im 14 years old, and i am fully developed, 120 lbs, and have been since i was about 11 years old. theres no reason why i shouldnt have my period, everything is in place. and my doctor said i should get it “any day now” four years ago

    1. scweetci_87bc

      Yes. There are several disorders where the female is born infertile, or so close to infertile that it is rare for them to ever have a child.

      Some disorders that cause infertility are : Turner’s syndrome, Down Syndrome, Polycystic Ovarian Syndrome,systemic lupus erythematosus, autoimmune hypothyroidism, and autoimmune Addison’s disease,Adrenal, pituitary, or thyroid gland deficiencies, Genetic factors related to the X chromosome, genetic defects in the production of growth factors called inhibins produced by the ovaries, Luteal phase defect, fibroids, Hyperprolactinemia, Underdeveloped reproductive organs, underdeveloped or missing fallopian tubes, mother being treated for cancer while pregnant or infant being treated for cancer with certain medications, mother taking certain medications while pregnant, or Syndrome X.

      What makes your think you were born infertile?

      Note: Sometimes with reproductive therapy it is possible for someone who is infertile to produce a child, but it is rare without medical assistance.

  7. tommysgrl78

    can me and my husband conceive a child even if both of us have autoimmune diseases?
    i have lupus and he has colitis. I have done some reasearch on his medication and it doesn’t say anything about infertility. But i have heard that it could be diffucult to concieve. Is that true?

    1. mgnysgtcappo

      Conception isn’t usually a problem with Lupus patients however, carrying a baby to term can be. Many of the medications you take for your Lupus are very harmful to a developing fetus. The only medication used to treat Lupus that directly causes infertility is Cytoxan.

      One major issue is whether or not you’ve been checked for APS or Antiphospholipid Syndrome. This is a disease that over 50% of Lupus patients have but only 25% of them are actually tested for it. APS is a blood clotting disease which can cause blood clots to form causing an embolism, heart attack or stroke. It is a DEADLY disease. It has been linked to death during childbirth.

      You must get tested for this disease. It is a simple blood test but unfortunately many doctors never test for it due to lack of education. Demand this test before you decide to get pregnant. If you have it then you should really consider alternatives to becoming pregnant, such as surogacy or adoption.

      The last problem with Lupus is the higher incidence of Miscarriage. This can be caused by APS as well. All pregnancies with Lupus will be considered high risk and you must consult with a specialist OB/GYN BEFORE you get pregnant.

      All Lupus pregnancies should be planned. You should make sure to time the pregnancy during a long remission period as you may be able to change your medications during this time.

      Please make sure to consult your doctor before making any decisions on pregnancy.

      Oh and by the way, the person above me who said that you should consider the baby getting your disease, less than 3% of babies born to mothers with Lupus actually get the disease. It isn’t considered a ‘genetic’ disease. It is believed that both genes and environmental factors contribute to Lupus.

      Good Luck to you

  8. average cabbage

    could an abusive childhood cause lupus/autoimmune diseases?
    I’m 17 and have lupus. I’ve been told that excessive stress can cause it. I know Michael Jackson had lupus and had an exceptionally stressful childhood. I was physically abused as a child so could it have contributed? My family doesn’t have a history of autoimmune diseases so I don’t know how I got it.

    1. The Know It All :-P

      Stress cause “flares” of lupus, but it doesn’t actually give you lupus. Chances are there are hidden autoimmune disorders in your family that no one is aware of.

      Take good care of yourself and hopefully you will be able to manage it well..

  9. phreadriquebean

    Do I have any hope of becoming a doctor?
    I have always wanted to be a doctor! But growing up I kept getting sick. I’m 24 now and a sophomore in college. I’ve been diagnosed with 4 different autoimmune diseases in addition to allergies and asthma. Over the last 2 years, I have been extremely ill with new symptoms including debilitating fatigue (lots of ideas, no real explanation yet). I had to drop all of my classes last fall (resulting in a 0 GPA for one semester) and am now trying to rebuild my GPA (a 3.75 when I transferred from community college). I work in a health related field about 30 hours per week (to pay for all my freaking medical bills and medications, not to mention school). Between work, class, and being sick all of the time, I haven’t gotten involved with any extra curriculars or volunteer time. I’m 100% certain I have the dedication and work ethic to be a doctor. I’m worried that I won’t be able to compete to get into med school if I continue to be sick like this all of the time! Should I keep trying?

    1. christibro40

      Hi, Im Chris I have 4 or 5 autoimmunes as well. so I know where you are at, the difference is I am 40, I have children close to your age. Though undiagnosed at your age I did get through college but with a merchandise marketing degree with a 3.5 GPA and a baby as a single mom at the time.
      Right now, I have Lupus, Autoimmune Hep, Sjogren’s, Raynaund’s, and I’m getting over cebritis of the brain, and RSD.

      I know for a fact you can do it. I co-own a Lupus/autoimmune support group. We have a girl in her Freshman yr of college with the same goal. Since her Freshman yr, she is able to take many of her classes online. can you take some non-pre med or electives online?

      Also, though it may take a bit longer, by lowering your load by 1-2 classes, may help a bit, and raise your GPA at this point before med school. Med school is punishing. also there are different areas of medical practice, some less grueling and less germ exposing.. Medical research, nuerology, and hey Rhuematology come to mind instantly.

      Pediatrics, surgery, and a few others are out. I know many rhuemies have autoimmunes of varying degrees. They make the best rhematologists, and tend to look outside the box. I havent openly asked mine, but I think she has one that is well controlled, she keeps herself well paced, daily schedule to a limited amount of paitents (i never wait more than 10 minutes) and always looks outside the box, unlike other Rhuematologists. My bloodwork is not always the best indicator of disease activity, but she has been my Rhuemy 10 yrs, so can see any small change in behaivor, butterfly rash, etc. In fact she dx cebritis and got me on chemo and saved my life when the blood test where inconclusive. I think you would be that kind of doctor, instinctive….

      Just remeber Med-school and recidancy is high paced, many hours, no rest, demanding etc. so you would have to have great control by that time, but if you went into rhuematology you have inside information; you have 4 connective tissue diseases/ or other autoimmune diseases.

      I land in the hospital or with a major flare either 1x a yr or every other year. I thought I couldn’t do anything. Now I need some work, and have someone working as an editor for me, But I write. Mainly non-fiction medically based articles. one has been published. The others, need a fine tooth comb, lol before I will submit. A huge change from retail mgt and buying but better. I also co-own, do research for and write articles for a very busy yahoo groups support group. I belive (oh I use spell check a lot, this spell check is hard to use) even with illnesses like ours, with the right attitude, proper pacing, and ambition we can do it.

      I do know as a Resident, and Med-Student you won’t be cut much slack, But if you make it through that, and go into a partnership or private practice, YOU decide how small or big you want the practice. If you want 60 people cheering you on to get to your goals to be a doctor. My group will be your largest cheerleaders, and we will give you a major brain workout, lol asking all kinds of medical questions.

      Medicine is Honorable, escpesially if done for the right reasons. Just cut back, for now, find ways to gain some energy.. I know some hints for energy that wont harm you, thanks to my dr. Tthere is nothing you can’t achieve. As long as your entire body dosnt give like mine tends to. Remeber though I am a lot older. So right now your my hero for trying. I would try If I didnt have a teen, so many flares, and wasn’t ugg, the thought!!! middle age.
      Good luck

  10. cutie101angel97

    When does Miley Cyrus going to air the new episode: No Sugar, Sugar?
    It said it was going to air like a week ago but it never did. So i was just wondering.

  11. kim a

    My 5 year old daughter has chronic ITP and I am wondering if anyone has information that may help us?
    My daughter has had a platelet count around 20,000 for the past 2 years with small fluctuations here and there. I am worried that she may have the start of an autoimmune disease since I have rhuematoid arthritis.

    1. chafarm123

      Idiopathic Thrombocytopenia, or ITP, as you probably already know is a disorder of chronic episodic low platelets, of unknown cause. Despite this, many physicians feel it does have an autoimmune basis. I have had a patient, when in training who developed this following a MMR (Measles, Mumps and Rubella) immunization. The most important thing, which you have likely already done, is to rule out other causes for thrombocytopenia (low platelets) such as leukemia, systemic lupus erythematosus, an enlarged liver, and something called anti-phospholipid syndrome.
      Japanese researchers have explored a link between ITP and Helicobacter pylori,(a bacterial stomach infection) as a causation of some ITP. H. pylori is treatable, and so this also should be tested for, and ruled out.
      The safest and most complete management for your daughter would likely be at a major university medical center. She should have a board certified pediatrician who can carefully consider her immunizations as she moves through childhood,and take careof routine issues, and a board certified hematologist who will be available to both you, and your pediatrician to follow your daughter and consult as needed.
      All of the patients I had who had ITP as children, are alive today. Best wishes.

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