WHAT IS PEYRONIE'S DISEASE?The plaques are hard, thickened and stiff areas, actually a kind of internal scarring. In this fibroid tissue also calcium compounds can accumulate, making the plaques even harder.


The three main characteristics of cavernositis are:

– One or more small hard lumps underneath the skin, or a continuous hard, stiff and thickened area.

– Abnormal bent or crooked penis when erect. All penises have some curvature, but by this disease, the penile bend increases, and one may get a very curved penis. The penis may be bent as a banana or in an angular fashion. The penile bending is most often up, but may be down, to the left side, to right or sloping.

-The bending is usually to the same side as that of the hard thickened area when the penis is erected.

-The hard areas in the erected penis may look like bumps, making the penis irregular.

– Sometimes the penis bends greatly enough to make sexual intercourse difficult, or impossible.

– Pain during erections caused by the pressure from the hard areas in the penis, or from the


The exact cause of the induration is unknown. It's not a sign of an underlying serious condition, and it is not a sexually transmitted infection. It is possible that the disease can begin with an inflammation in the penile tissue. An inflammation may be caused by an allergic or auto-immune reaction. Although the Peyronie's disease is not an infection, an initial infection can damage the penile tissue and cause an inflammation that develops into Peyronie's disease. Men having the inflammatory condition called Systemic Lupus Erytematosus more often get Peyronie's disease.

Vitamin E deficiency seems to be a contributing factor in causing the disease. Diabetes may cause damage of blood vessels, and if this damage occurs in the erectile bodies of the penis, Peyronie's disease can develop. Peyronie's disease is sometimes a side effect of the drug Inderal (propanolol) used against high blood pressure.

Sometimes a physical injury to the penis that causes internal bleeding, or a series of such injuries, is the initial cause. A habit of violent sexual activity may cause such injuries. It is thought that some men may have a genetic disposition to the condition.

Plastic induration of the penis is not a cancer, and cannot cause cancer, however a lump or deformation in your genitals that develops, must be examined.


Not all men with Payronie's disease require treatment. The disease sometimes go away by itself. If the condition is pronounced, it is also difficult to find a remedy that can cure every sign of the disease, but several methods can take away most penis changes associated with Peyronie's. Here is a survey of treatment methods used today.

Tamoxifen – In its early stages of the disease a medication called Tamoxifen has been shown to prevent the formation of the fibrous plaque by Peyronie's disease. This drug is also used in the treatment of breast cancer, but the two conditions are not related.

Vitamin E and B – Vitamin E and B is sometimes effective in easing the pain and as a treatment for the penile deformity by Peyronie's disease.

Verapamil – Verapamil, often used in the treatment of high blood pressure, has been shown to decrease the size of the plaque and decrease the pain when injected directly into the plaque, and thus also improve the penis shape distortion by peyronie's disease.

Shock wave therapy – Extracorporeal shock wave therapy, or ESWT, a new treatment, is being used in some hospitals for the Peyronie's disease. Although the initial results of this new approach to treat Peyronie's disease have been promising, the long-term outcome is still undetermined.

Surgery – This is sometimes considered if Payroni's disease has lasted for a year or more and it hasn't progressed or regressed for at least three months. By the Nesbitt procedure one removes tissue opposite to the curve to straighten the penis. Another procedure involves putting a graft or part of a vein within the fibrous plaque to lengthen this area. In certain cases of Pyrenees disease, surgical insertion of a penile prosthesis (implant) is recommended.

Radiation therapy – This treatment modality has been tried, but the results are unpredictable and sometimes the opposite of the intended one.

Traction devices – On the market, you can buy mechanical devices to use on the penis some time daily that gently pull upon the penile tissue to straighten out the penis, and thus mending the penis from the curvature caused by Peyronie's disease.

About the author:

Source: http://www.sooperarticles.com/health-fitness-articles/men-health-articles/peyronies-disease-abnormally-bent-penis-causes-symptoms-treatment-options-19688.html

early lupus signs

8 thoughts on “Early Lupus Signs

  1. Speciall Buchanan

    I had a mri done May 2009 and doc said i have spots on my brain and dont worry its probly allergies is this t?
    I have sharp pains that hit in my brain constantly,and near my temple, my heart skips beats, I miss my period for 4-6 months at a time, I get sharps pain in my left hand, and my feet swell. My hair is also fallen out. What is wrong with me?

  2. caring mother and grandmother

    What does Grade 2 placenta mean at 18 weeks of pregnancy? How dangerous is this for the mother and baby?
    My niece has just received word from her OB/GYN that her ultrasound showed that her placenta was at a Grade 2. At the time of her ultrasound she was only 18 weeks.

    1. camarolynk

      Grade 2

      Late 3rd trimester (~30 wks to delivery)

      Larger indentations along chorionic plate

      Larger calcifications in a “dot-dash” configuration along the basilar plate

      Grade 2: The mother is symptomatic but not in shock. There is some evidence of fetal distress can be found with fetal heart rate monitoring.
      I’m not entirely sure what exactly the standards are for grading a placenta but placentas are graded 1-3 based on calcifications. In general, at term, most placentas show some signs of calcifications and would be a higher grade. It wouldn’t be uncommon for a term placenta to be graded a 2, but at 32 weeks it is concerning. Earlier in the pregnancy, calcifications can be a sign of early placental insufficiency. It is more common in women with high BP, and also in diseases like lupus. Lupus is a particularly scary thing to be pregnant with, since the disease can cause abnormal blood clotting, including in the cord and placenta. Also, babies whose moms have lupus can be born with congenital heart block, a very serious cardiac condition. It is one of the few illnesses that necessitate very close observation and even early delivery to protect the baby.

  3. Lelani

    How do you tell a friend your sick?
    I’ve been battling a mystery illness off and on for about a year and a half. The Drs think it’s an early sign of MS or Lupus or some other autoimmune disease.

    Recently I people have been noticing I have been “down in the dumps” but I’m not really…I’m just in pain and don’t feel well although I am happy on the inside. How do I tell this to a friend? What other people should I tell this to? (I’m in college)

    I don’t like people worrying about me or feeling sorry for me….

    1. Mosie

      Just say exactly what you have said here that your kinda tired and ur being investigated but you have no idea what it is…at the end of the say its ur business nobody elses!

      Hope u get sorted!

  4. Snowboarder

    Confused about conflicting signs from cervical position and cervical fluid?
    I had stretchy clear ewcm but yet my cervix felt hard. This was Monday and Tuesday. Do you think I ovulated? I’m confused because of my cervix. Usually when women ovulate their cervix becomes soft right? How long does it stay soft for? Is it possible for your cervix to only stay soft for a few hours during ovulation then get hard again? I had sex on Saturday so I’m wondering what the chances are that I ovulated and that I am pregnant.

    1. Starcatcher

      Don’t use cervix position as an indicator. Progesterone levels are what cause the cervix to soften. Not all women get high enough progesterone levels before ovulation to cause the softening of the cervix (don’t be concerned with that) but you should notice that it will be soft prior to when af is due and that the cm turns creamy or lotion like. This is because once you ovulate, the c. lupus begins making progesterone. It stays soft until close to af unless you’re pregnant in which it stays soft until labor.
      Go with the CM. You get the ewcm, clear, watery or stretchy cm when you are in your fertility window. Remember you can have fertile cm for up to 6 days — Nature’s way of making sure sperm have a way to reach the egg. You want to bd on the days of your fertile cm and the day after (most women can still conceive the day after their lh surge if they bd early that day).

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