Many people that have halitosis don't understand where it comes from. They practice superior oral care, have no oral conditions or diseases, stay away from odorous foods and abstain from smoking. In cases like these, many times the halitosis can be explained by medical conditions or diseases the individual has completely unrelated to their mouth.
According to the Mayo Clinic, approximately 10% of halitosis cases are rooted in issues not involving the mouth whatsoever. These cases are known as extra-oral halitosis. Sometimes odorous breath is actually a warning sign that there is a deeper medical issue at stake.

Metabolic Diseases

Metabolic disorders occur when the normal metabolizing process is disrupted by unusual chemical reactions in the body. There are a number of metabolic disorders that would cause bad breath. Certain metabolic diseases that create bad breath are diabetes, liver failure and kidney disease. This is because the equilibrium of electrolytes and other bodily chemicals is imbalanced. Diabetes generally creates an acetone or fruity smell, while liver failure tends to have a sweet or musty smell. In liver conditions such as cirrhosis, it may result in a urine-like odor.
Trimethylaminuria is a relatively rare condition that may produce fish odor as it creates an improper production of the enzyme Flavin containing monooxygenase 3.

Autoimmune Diseases

There are a handful of autoimmune diseases that may also cause bad breath. Sjogren's syndrome is an autoimmune disease that causes Xerostomia, or intense dry mouth, which can cause worsening of breath odor. Other autoimmune diseases like Hashimoto's thyroiditis and lupus can cause bad breath.


Odorous breath may also be a symptom of cancer. Cancer of the lungs, esophagus, tongue, mouth, pharynx or larynx can all cause foul odors when breathing. If you are experiencing pain in these areas, bleeding from the mouth, coughing or difficulty swallowing, you will want to see a doctor with your conditions.

Chronic Sinusitis, Post Nasal Drip & Allergies

Many times people with chronic sinusitis, sinus infections, post nasal drip or allergies are affected by bad breath. Problems with your sinuses generally causes inflammation in the nasal passages. The inflammation creates a narrowing of the passages disallowing the healthy flow of mucous and bodily matter. The trapped matter attracts sulfur-excreting bacteria that lead to bad breath.

Medications that Induce Halitosis

Some of the most frequently used prescription drugs have side effects related to bad breath, dry mouth or taste disorders. While the issue the medication is solving may be more important than minor bad breath, identifying what is causing your oral malodor may help you make a better decision for yourself. A few of the common medications that cause bad breath are:
Blood pressure medication – Zocor Anti-deppresants – Prozac, Zoloft Antihitamines – Claritin Cold medications
If you or a loved one suffers from medical-induced halitosis, there are solutions for you. You can visit the bad breath clinic to isolate the problem and find a solution. You may interested in home care solutions. The Center for Breathcure has a variety of products from dry mouth remedies to Oral B Sonic Toothbrushes!

About the author:


drug induced lupus syndrome

19 thoughts on “Drug Induced Lupus Syndrome

    1. Miguel Sanchez

      DPLD may be classified according to the cause: –

      Inhaled substances
      Hypersensitivity pneumonitis
      Drug induced
      Chemotherapeutic drugs
      Antiarrhythmic drugs
      Connective tissue disease
      Systemic sclerosis
      Systemic lupus erythematosus
      Rheumatoid arthritis
      Atypical pneumonia
      Pneumocystis carinii pneumonia
      Idiopathic pulmonary fibrosis
      Hamman-Rich syndrome
      Lymphangitic carcinomatosis

  1. Galavanting Gal

    Lawsuit against the drug Minocycline?
    Someone Named “Mom” wrote the following post 3 years ago. I am trying to find her and find out what happened because the exact same thing has now happened to me…

    Lawsuit against the drug Minocyline?
    Ten years ago my dermatologist prescribed me Minocycline for my acne (I was 15). A year or so later I developed ‘Drug induced lupus erythematosis’ because of the drug Minocycline. It was horrible. I spent the last two years of high school in chronic pain. I couldn’t shower or use the rest room alone… It was just horrific… After months of doctor visits and gallons of blood (not really, but it seemed like it) being drawn they realized what was wrong and I stopped taking the pill (minocycline) and recovered almost as good as new. Other than joint stiffness now and then.

    Just recently (within the last year) my husband and I encountered several failed pregnancies. The underlining cause was drug induced lupus because of the prescription, Minocycline. The lupus causes my blood to clot, which kills the fetus.

    My question is this… How do I create a law-suit against the prescription company?
    3 years ago Report Abuse Additional Details
    The blood clotting is the result of antiphospholipid syndrome, which I have because of the lupus. I should have mentioned that before.

    On the reasearch I have done (which is limited to googles search engene) I have read of others contracting lupus as a result of the drug, but nothing about lost pregnancies. I need to do more digging…

    But as far as my doctor just giving me some random cause for my lost pregnancies, this is SOOO not the case. I have had 3 different doctors say “yes you do have antiphospholipids in your blood” and with blood thinners you may be able to carry a pregnancy to term. Which has happend (I am now 8 months along)

    I really appreciate your advice!!!!!

    1. Gracie

      I was prescribed Minocin as a teenager for acne, my liver failed, I received no compensation, but I’m in the UK. It is only by the grace of God that I’m even alive to tell the tale. I’m sorry you’ve had such a bad time.

      Firstly, you need to find a specialist lawyer, they will listen to your case and there will be ‘buzz words’ key things they are looking for to assess whether or not you have a case. If they think you may have a case, they will as their own doctors to look you over and check your medical history, if they too believe that you have a case then the lawyers will take it from there.

      A class action, is when they look for others in a similar position to yourself in order to strengthen the case, if there is such a case then you need to see if you can add your name to the list.

      I would say though, that a law suit is very long winded and stressful, and if you have a young baby that is the last thing you need, not to mention stress makes lupus much worse, so maybe that is something you should consider?

      Good luck, I wish you all the best for the future and your new baby.

  2. angelinaismywifey

    dry skin, odd scarring bumps on face, neck, back and raynauds syndrome…..what could this be!?
    scaly hands and thickened skin on hands and feet
    swelling of any possible joint
    circulation problems and changes
    abnormal amounts of grey hairs all of a sudden
    weight loss
    gastrointestinal problems
    itchy skin!

    etc! i cant get a diagnosis i wanna say its lupus but w/ a rash that is noticable to everyone else …

  3. Koter Boters misses Rufus!

    what causes a low blood platelet count?
    I found out today that My blood platelet count was low and my hemoglobin.

    Could anemia be the cause of this? I have to do labs for this so they could tell if I am anemia or not but was wondering what causes blood platelets to go low.

    1. norton g

      Koter – Low blood platelet count is known as “thrombocytopenia.” Thrombocytes is another word for platelets while “-penia” means reduced or low numbers.
      Normally, you have anywhere from 150,000 to 450,000 platelets per microliter of circulating blood. Because each platelet lives only about 10 days, your platelet supply is continually renewed by production of new platelets from your bone marrow.
      If for any reason your blood platelet count falls below normal, the condition is called thrombocytopenia. Complications may range from none at all to severe bleeding. The risk of bleeding increases as the number of platelets decreases. The greatest risk is when platelet count falls very low — below 10,000 platelets per microliter. At this point, internal bleeding may occur despite a lack of any injury, although this is rare.

      Causes of thrombocytopenia generally fall under one of the several categories below.

      Reduced production of platelets
      Platelets are produced in your bone marrow. A medical problem that involves your bone marrow, such as occurs with leukemia and some types of anemia, could lead to a reduction in the number of new platelets produced. Viral infections, including HIV infection, may suppress your bone marrow’s ability to make platelets. Other cancers that affect bone marrow, chemotherapy drugs and heavy alcohol consumption also can impair platelet production.

      Increased breakdown of platelets
      A number of conditions can cause your body to use up or destroy platelets more rapidly than they are produced, leading to a shortage of platelets in your bloodstream. Examples include:

      ■Pregnancy, which may cause mild thrombocytopenia.
      ■Idiopathic thrombocytopenic purpura (ITP), a condition in which your immune system mistakenly identifies platelets as a threat and forms antibodies that attack them.
      ■Other autoimmune diseases, such as lupus or rheumatoid arthritis, which may lead to destruction of platelets due to a malfunctioning immune system.
      ■Blood poisoning from severe bacterial infections (bacteremia), which may lead to destruction of platelets.
      ■Thrombotic thrombocytopenic purpura (TTP), a rare, life-threatening condition that occurs when small blood clots suddenly form throughout your body, using up large numbers of platelets. TTP sometimes happens as a result of a genetic deficiency, but more often the cause is unknown. In some cases, it may be associated with infection or a chronic illness.
      ■Hemolytic uremic syndrome, another rare disorder that causes a sharp drop in platelets, destruction of red blood cells and impairment of kidney function. Sometimes, this can occur in association with a bacterial Escherichia coli (E. coli) infection, such as may be acquired from eating raw or undercooked meat (often hamburger).
      Certain medications can cause a thrombocytopenic reaction by confusing the immune system and causing it to destroy platelets. Examples include heparin, quinidine, quinine, sulfa-containing antibiotics, some oral diabetes drugs, gold salts and rifampin.

      In some cases, heparin-induced thrombocytopenia can cause excessive blood clotting instead of bleeding, increasing the risk of clot formation deep within a leg blood vessel or the transport of such a clot to your lungs, which can be life-threatening.

      Trapping of platelets in the spleen
      The spleen is a small organ about the size of your fist located just below your rib cage on the left side of your abdomen. Normally, your spleen works to fight infection and filter unwanted material from your blood. An enlarged spleen — which can be caused by a number of disorders — may harbor too many platelets, causing a decrease in the number of platelets in circulation.

  4. frauline2470

    What bad does caffeine do to our body?Immunity funtion disorder.What does it mean?
    My health result appears to be weak and may be a concern.

    1. PasoFino

      Signs and Symptoms of Caffeine Intoxication or Abuse

      nervousness, headache, increased heart rate, anxiety, upset stomach, irregular heartbeat, irritability, GI irritation, elevated blood pressure, agitation, heartburn, increased cholesterol, tremors, diarrhea, nutritional deficiencies, insomnia, fatigue, poor concentration, depression, dizziness, bed wetting.

      Caffeine Withdrawal Symptoms

      headache, constipation, runny nose, craving, anxiety, nausea, irritability, nervousness, vomiting, insomnia, shakiness, cramps, fatigue, dizziness, ringing in the ears, depression, drowsiness, feeling hot and cold, apathy, inability to concentrate


      Many disorders of the human immune system fall into two broad categories that are characterized by:

      Weakened immune response:

      There are ‘congenital’ (inborn) and ‘acquired’ forms of immunodeficiency, characterized by an attenuated response. Chronic granulomatous disease, in which phagocytes have trouble destroying pathogens, is an example of the former, while AIDS (“Acquired Immune Deficiency Syndrome”), an infectious disease caused by the HIV virus that destroys CD4+ T cells, is an example of the latter. Immunosuppressive medication intentionally induces an immunodeficiency in order to prevent rejection of transplanted organs.

      Overzealous immune response:

      On the other end of the scale, an overactive immune system figures in a number of other disorders, particularly autoimmune disorders such as lupus erythematosus, type I diabetes (sometimes called “juvenile onset diabetes”), multiple sclerosis, psoriasis, and rheumatoid arthritis. In these, the immune system fails to properly distinguish between self and non-self, and attacks a part of the patient’s own body. Other examples of overzealous immune responses in disease include hypersensitivities, such as allergies and asthma.

      Other factors that affect immune response:

      Many factors can also contribute to the general weakening of the immune system:

      Malnutrition (unbalanced diet / poor eating habits that cause a lack of vitamins, minerals and Polyphenol antioxidants)
      Alcohol abuse
      Drug abuse either intravenous or other. (Appears related to associated factors i.e. poor diet, use of infected/dirty needles, poor exercise, stress/depression)
      Medications (particularly the use of anti-cancer drugs, corticosteroids, and antibiotics);

      Exposure to certain environmental toxins, whether naturally occurring or from pollution. These include:
      Cigarette smoke
      Stress/Depression – Research shows that psychological stress can greatly increase your susceptibility to colds and other viral diseases, namely through an increase in serum corticosteroid levels
      Age – Ability of the immune system to respond is decreased at early and old age.
      Decrease ability to heal due to disease or medications (i.e. Diabetes, corticosteroids, immune suppressant drugs), causing constant exposure to infectious agents without natural defense (intact skin)
      Inadequate sleep at the Delta brain wave level. According to a sleep study, we need 4 hours of Delta sleep every night
      Lack of exercise as well as excessive exercise resulting in physiological stress
      Long-term weightlessness

      Diseases either infectious or other causing more depression on the immune system like:
      Cancer, and hematological malignancy (such as leukemia, lymphoma and myeloma) in particular.
      Diabetes Mellitus
      Cystic fibrosis
      Lupus Erythematosus
      Nephrotic syndrome
      Viral infections i.e. viral respiratory infections then allowing for bacterial pneumonia to develop.
      Ulcerative colitis
      Bulimia (due to malnutrition, stress, depression).
      Sickle-cell disease.
      Liver disease / cirrhosis
      Cushing’s syndrome
      Huntington’s Chorea

  5. 600pm

    What is paranormel activty? how can i trigger it?
    Why do i hear vocies cuss no one was hear in the apartment and no one had a tv on so how am i hearing voioces they are evil vocies so hearing voices when no one isa round called?

    1. irenaaneri1980

      Its not necessary a sign of schizophrenia.
      It can also be a sign of “spiritual” activity.Although some people might not believe in it is does not mean it doesnt exist as in the same way some people might not believe in God but He still remains in existance regardless of whether we believe or not-He is not limited by our beliefs.

      First and foremost,you dont want to be “triggering” or encouraging spiritual activity as that can be dangerous.There is absolutely no need for it and could cause you more harm then good so its better not to “mess” with it.
      If your young it might seem fun or whatever but there a lot of fun you can have with “real” people instead of “triggering” spiritual activity

      Secondly,does anyone else here these voices and/or are they limited to your apartment?
      If someone else hears them or you find that its only in your apartment you hear them but nowhere else then that is more of a chance that it could be “”paranormal” activity in which case i’d suggest to get in touch with a good church and mention what you perceive is happening and hopefully they will send out a priest to investigate

      If however,you hear these voices in other places too and not limited to only your apartment then there could be a chance that this actually is a illness process.
      I wouldn’t be so quick though to jump at the conclusion of schizophrenia but first make sure that there isn’t an organic cause causing this such as TLE,Encephalitis,Cerebral syphilis,porphyria,Central nervous system infections,Wilson’s disease,Brain tumors,Lupus,Cushing’s syndrome,subdural haemorrhage,Thiamine deficiency-there are other things too.
      Also if you are over 45 years of age there are some other disorders that need to be investigated into also.

      Only then after all possible organic causes have been ruled out look into the possibility of schizophrenia,which if by some chance it was,there are medications that can be effective for the symptoms

      The only other thing i can think of is if you are abusing alcohol or drugs like some of the kids who ask questions here on this board then that could be the cause-a drug induced psychosis- and you shouldnt be surprised that abusing drugs can cause this.Im not saying that necessarily applies to you but just to anyone who does that to be aware that this can happen

  6. ★☆✿❀

    Does this sound like Sjögren’s Syndrome?
    Im 21 years old. I have celiac disease, hypermobile syndrome, asthma and raynauds.

    Since I was 8 years old I’ve been experiencing flare ups of achy, stiff swollen joints. Before this year, I’d have a flare up once every two years or so and then I’d go away.

    In October last year I started getting swollen, sore, stiff knees and fingers. This progressed to my toes, shoulders and hips. I developed a dry mouth when I was about 15 years old and ever since I have drunk about 1.2 gallons (4.5 liters) of water each day. In April this year, over night I developed dry, burning, gritty eyes. I also have nose ulcers, fatigue and vaginal dryness. My skin is not overly dry. I have joint pains but no muscle pains.

    I have a positive ANA, in the past year my ESR has been elevated a few times. Everything else (full rheumatological work up) was negative.

    I saw a rheumatologist who said she thought it was fibromyalgia (which I told her I disagreed with). She thought maybe drug induced lupus (although my recent flare up started before the medication). She thought reactive arthritis, but I’ve had no infection. She completely dismissed the possibility of it being Sjögren’s.

    I got sent to an Ophthalmologist. He said I have severely dry eyes and scaring from the dryness. My schirmer test was normal but the orange and green dyes and whatever he could see when he looked at my eyes apparently told him they were very dry. He wanted to put plugs in but I wasn’t so keen. He said I definitely have Sjogrens with an overlap of Rheumatoid Arthritis.

    I’m so confused. The rheumatologist is humming and harring and I’m getting worse. There are no other rheumatologists for at least a 5 hour drive away. The opthalmology will only treat my dry eyes but my joint problems are fatigue are my biggest complaints.

    Any advice?
    Oh and I have vasculitic rashes. My GP said they’re very common in autoimmune diseases. And my SSA and SSB were negative. But it was done after a course of prednisone and I was completely symptom free at the time. The rheumatologist said the prednisone would have had an impact on my blood test results, yet she still ordered them and now she won’t reorder them!

    1. Linda R

      If you want to feel better, you will have to drive the distance to see another rheumatologist. No one here can solve your problem. You need a doctor who will work with you.

  7. Mrs. Bitch to you

    Help with these blood test results please?
    Hi there, I went to see my rheumatologist today and he won’t be in till Friday which is my birthday.. I honestly don’t want to have any rotten surprises on my birthday so I was wondering if anyone could decipher these results for me:

    Anti-Dna (1:10 DILUTION): Negative

    ENA: *

    NRNP/SM Negative
    SM Negative
    SS-4 Negative
    Ro-52 Negative
    SS-B Negative
    SCL-70 Borderline
    PM-SCL Negative
    Jo-1 Negative
    Centromere B Negative
    PCNA Negative
    DSDNA Borderline
    Nucleosomes Borderline
    Histones Negative
    Ribosmal-P-prot Negative
    AMA-M2 Positive +
    Control Strong Positive +++

    What the heck does this all mean? I looked it up online but got nothing of much use.

    Thank you sincerely for any and all help.

  8. Koter Boters misses Rufus!

    What can you tell me about Polyglandular auto-Immune Syndrome?
    What kind of diet should I be on? How do you get it?

    any other info?

    Type 2.

    Im only asking caise it was writteon my discharge papers but not explained.

    1. Starlet

      I could only find info on Autoimmune Disease: Any of a number of disorders in which the immune system produces antibodies that attack one or more of the body’s own tissues. These tissues act as as Antigen(protein that stimulates antibody production) & the resulting antigen-antibody reaction damages the tissues or disturbs their function. The tissues that act as antigens may be confined to one organ(for example the thyroid gland in Hashimoto’s thyroiditis) or widespread throughout the body(as in systemic Lupus erythematosus & Rheumatoid Athritis).
      Causes: The immune system normally distinguishes ‘self’ from ‘non-self’ (foriegn tissue). The exact cause of the autoimmune response is not completely understood, but four possible mechanisms are recognised.
      Hidden antigens(such as substances normally within cells) may induce antibody production if they are released into the circulation.
      ‘Self’ substances may undergo chemical, physical or biological change & become antigens. For example, certain drugs can combine with body proteins to stimulate antibody production, and in Photosensitivity ultraviolet light alters skin protein, to which the pateint becomes allergic.
      ‘Non-Self’ antigens may induce antibody production that cross-reacts with ‘self’ antigens.
      Production of antibodies against ‘self’ tissue may result from a mutation in, or disturbance of, the normal control of the lymphocytes(white blood cells) that form antibodies.
      Treatment: Autoimmune diseases are treated by correcting any deficiencies they cause(such as replacing thyroid hormone in hashimoto’s thyroiditis), & measures to reduce the activity of the immune system(such as Corticosteroid Drugs and, in severe cases, Immunosuppressant Drugs.
      I might do a write up on glandular fever later, got to take a break.

    1. Gellar

      Prednisone can be used in autoimmune diseases, inflammatory diseases (such as severe asthma, severe allergies, angioedema episodes, severe urushiol-induced contact dermatitis, systemic lupus erythematosus, ulcerative colitis, rheumatoid arthritis, Bell’s palsy, Crohn’s disease, pemphigus and sarcoidosis), uveitis, various kidney diseases including nephrotic syndrome, mononucleosis Epstein-Barr virus, and to prevent and treat rejection in organ transplantation. Prednisone has also been used in the treatment of migraine headaches and cluster headaches and for severe aphthous ulcer (“Cankersore”) outbreaks. It can also be used to treat autoimmune pancreatitis.

      Prednisone is used as an antitumor drug. Prednisone is very important in the treatment of acute lymphoblastic leukemia, Non-Hodgkin lymphomas, Hodgkin’s lymphoma, multiple myeloma, and other tumors in combination with other anticancer drugs.

      Furthermore, the pharmaceutical industry uses prednisone tablets for the calibration of dissolution testing equipment according to the United States Pharmacopeia (USP).

      Intravenous application may be employed for cerebral inflammation, as in the periodic attacks caused by multiple sclerosis.

      Prednisone is also used for the treatment of the Herxheimer reaction which is common during the treatment of syphilis, and to delay the onset of symptoms of Duchenne muscular dystrophy. The mechanism for the delay of symptoms is unknown.

      Because it suppresses the adrenals, it is also sometimes used in the treatment of congenital adrenal hyperplasia.

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